It’s way too early to tell. I think WotC engendered enough ill will among those folks that every move they make is viewed negatively.
On the other hand, folks who didn’t hate on 4E, or who actually enjoyed it, are hopeful that lots of lessons have been learned, and that the promises of a more transparent development process will lead to a game that more people want to play.
After riding the twitter streams for a bit in the morning, I read the various mainstream media articles (Hey! Changes to D&D warranted a NYTime article? This IS the era of Geek.) and some prominent bloggers’ thoughts. The folks who were invited to a playtest all had positive experiences (I expect they were a sympathetic audience).
All things considered, I’m optimistic.